Based on my experience with my '13 R-D with 20s, I was very worried when we went with a '22 T8 R-D with 21"s without air suspension. Would have preferred 20"s but it is what they had. However, the stock suspension and ride is MILES better in the '22, even with the 21"s than my '13. Very happy without the air suspension.
Having said all that, I find the wheel size inflation crazy. When I got the '13 with 20" they looked huge compared to any car I ever had. Talking 21-22"s on a non-performance car just adds so much cost, maintenance, and hassle.